Actor Chloe Bennet (A.K.A. Chloe Wang), who currently stars on Nashville, will be playing Skye. Her character was described in the original casting call like this: “This late-20s woman sounds like a dream: fun, smart, caring and confident – with an ability to get the upper hand by using her wit and charm.”
Her’s is the only character from the casting call that isn’t listed as an ‘agent,’ which makes me think that she won’t be one at the start of the series (though I imagine that will change by the end of the pilot).
The previously announced cast members include Clark Gregg, reprising the role of Agent Phil Coulson that he played in numerous Marvel films; Ming-Na, of Stargate Universe and E.R. as Agent Melinda May; Brett Dalton as Agent Grant Ward; and Ian De Caestecker & Elizabeth Henstridge as Agent Leo Fitz and Gemma Simmons respectively.
The series is aiming for a Fall of 2013 premiere.