Thunderstruck Books took over the location formally held by Labyrinth Books and Games when the later closed its Toronto location.
The selection took a hit with the turnover, but Thunder Stuck has spent the time since its opening re-stocking and now has a good selection of mainstream comics, manga, and pops. One thing that sets this store (and its predecessor) is its selection of art books; a category ignored by most comic stores.
Make sure to follow them on facebook, as they have an occasional (and really good) store wide sale.
Address: 386 Bloor St. W. Toronto, Ontario